– Treatment with the highly selective NaV1.8 pain signal inhibitor suzetrigine met the primary endpoint with a statistically significant and clinically meaningful 2.02 point within-group reduction ...

VX-548 selectively inhibits NaV1.8, a voltage-gated sodium channel that plays a critical role in pain signaling in the peripheral nervous system. Treatment with oral VX-548 resulted in a statistically ...

Jonathan Wosen is STAT’s West Coast biotech & life sciences reporter. You can reach Jonathan on Signal at jwosen.27. Vertex Pharmaceuticals said Thursday that its closely watched drug, suzetrigine, ...

Numerical rating scale pain scores accurately measure pain intensity in relation to perceived need for medicine, pain relief and pain satisfaction in children, according to a study published in ...